Gentle Series

Modular automation, optimized for scale-up

Complete Flexibility in Process Design

CellBri’s Gentle Series delivers step-specific automation tailored to fit any workflow and scale as your needs grow.

Gentle Flex Pro

A closed automated cell processing system ideal for solid tumor applications and high-volume allogeneic workflows.
  • Multi-step capabilities: PBMC separation, magnetic bead incubation, viral transduction, washing, and dispensing
  • 50L sample volume support; up to 1E11 T cells
  • High-flow rate (up to 220 mL/min) with >90% recovery
  • FaSe™ fast separation tech for low shear, high viability
  • Integrated formulation and cryo dispensing (3 bags/batch)
  • 21 CFR Part 11-compliant

Gentle EXP

A fully enclosed, rocking bioreactor optimized for efficient, scalable expansion.
  • Tray capacity: 10L, 20L, 50L
  • Working volume 400 mL–25 L
  • Digitally controlled rocking speed, DO, pH, gas flow, and temperature
  • Cascade PID control with real-time alarms and audit trails
  • Ideal for both adherent and suspension cultures
  • 21 CFR Part 11-compliant

Gentle n-MagS

Nano-magnetic bead sorting for CD3+ and other target populations  
  • Fully automated, enclosed magnetic separation
  • 95% purity, >95% viability, >60% yield
  • Integrated flow sensors and inline weighing
  • Pairs seamlessly with Gentle Flex Pro for complete workflow automation
  • Approximately 45-minute run time
  • 21 CFR Part 11 Compliant

Gentle P-Pac

Automated fill and finish platform for viral and cell processing  
  • Dispense 2-150 mL per bag, up to 3L total per run (20 bags/cycle)
  • ±0.3–2% dispensing accuracy, <5% concentration variation
  • Maintains 2-8°C during fill to preserve cell viability
  • 10x faster than manual, ensures uniform bag integrity
  • Independent channels allow for simultaneous multi-volume dispensing
  • 21 CFR Part 11-compliant, GMP-compliant, Linux-based OS with preloaded protocols

Ready to Accelerate Your Cell Therapy Program?

Let’s build a faster, more reliable, 
and scalable process together.