About CellBri

Your Cell Therapy. Automated Your Way.

Committed to Making Cell Therapies Accessible

CellBri is redefining what’s possible in cell therapy manufacturing. As a pioneer in automated cell processing systems, we empower therapy developers and CDMOs to reduce cost, streamline timelines, and minimize risk without sacrificing flexibility or control – and without having to disrupt your existing processes. With deep roots in engineering and regulatory insight, we’ve created a cell therapy platform that grows with your needs, from early development to commercial scale.

Our Mission

To make life-changing therapies more accessible by simplifying and scaling how they are made. We believe in enabling the future of personalized medicine through automation that works for every team, every therapy, everywhere.

Global Presence

Headquarters

Shenzen, China

Consumable Manufacturing Facility

Changzhou, China

North American Operations

Los Angeles, CA & North Carolina

European Manufacturing
& Distribution

Hungary

Global Distribution Network

Across APAC, Europe, and North America

Why Cellbri

    Proven in 34+ GMP clinical and commercial programs
    Flexible modular, and all-in-one platforms that integrate with your existing processes
    Committed to compatible architecture – no locked-in reagents or consumables
    Trusted by leading biopharma innovators and CDMOs

Certifications
& Compliance

ISO 13485 Certified
FDA Registered
CE Marked
21 CFR Part 11 Compliant

FAQs

  • CellBri makes instruments that automate cell therapy manufacturing processes. We have modular instruments that can be integrated into workflows that automate specific unit operations, and we also have our all-in-one CellFAB One series of instruments that can be configured for a variety of workflows.

  • CellBri products are designed to have a high degree of compatibility and modularity to fit with diverse manufacturing environments. Our “no proprietary lock-in” philosophy allows for integration with both manual processes and other automated systems.

  • We have many off-the-shelf instruments that can be configured to fit most cell therapy processes. However, if you have a unique procedure that requires additional customization, our team of engineers would love to find a solution that addresses your needs.

  • contact@cellbri.us or message us on https://www.linkedin.com/company/cellbri/

  • The CellFAB One is an automated, fully integrated, and closed-system platform designed for the end-to-end manufacturing of cell therapies – such as Chimeric Antigen Receptor T-Cells (CAR-T), Natural Killer (NK) cells, T-Cell Receptor T-Cells (TCR-T), and stem cells. It supports cGMP compliance through three primary pillars:

    • Sterility Assurance: The functionally closed, single-use design eliminates contamination risks and allows for manufacturing in grade C cleanroom environments.
    • Process Consistency: Full automation of wash, isolation, expansion, and formulation removes manual variability and human error, ensuring repeatable batch-to-batch results.
    • Data Integrity & Traceability: Integrated software provides 21 CFR Part 11 compliant audit trails and electronic batch records, streamlining the Quality Assurance (QA) review process.

  • A closed system reduces contamination risk by keeping the biological product isolated from the surrounding environment throughout the entire manufacturing process. Instead of manual handling in an open-air environment, CellBri’s instruments utilize sterile, single-use disposable kits and airtight tubing sets. This ensures that the cells are never exposed to ambient air, microorganisms, or human-borne contaminants. By automating fluid transfers and processing within this sealed environment, the system minimizes the risk of batch failure due to environmental exposure or operator error.

  • We have validated our instruments to operate in a Class C cleanroom environment.

  • Yes, the software integrated into CellBri instruments is designed to be 21 CFR Part 11 compliant. To meet these regulatory requirements for electronic records and signatures, the system includes:

    • Multi-level User Access: Restricted access based on defined roles and permissions.
    • Audit Trails: Automated logging of all operations, parameter changes, and system events to ensure full traceability.
    • Electronic Signatures: Secure methods for approving records and validating processes within the digital system.

  • Batch reports can be easily exported as a PDF, CSV, or Excel file onto a USB drive. CellBri is in the process of enhancing its software to allow users to export batch reports through an ethernet connection as well.

  • CellBri instruments are manufactured to meet rigorous international standards for quality and safety. Key certifications and compliance standards include CE Marking (EU safety and performance compliance), ISO 13485 (international quality management standard for medical devices), and EU MDR (Medical Device Regulation) approval. In the United States, Device Master Files (DMFs) have been filed with the FDA for our instruments.

  • CellBri platforms are reagent-agnostic, allowing customers to use their preferred reagents, eliminating that variable when transitioning their workflows.

  • CellBri instruments and systems are designed to support both autologous and allogeneic cell therapy manufacturing. These platforms are currently being used with a wide range of therapies, including Natural Killer (NK) cells, Tumor-Infiltrating Lymphocytes (TILs), Chimeric Antigen Receptor T-Cell (CAR-T), T-Cell Receptor T-Cell (TCR-T), Induced Pluripotent Stem Cells (iPSC), and Mesenchymal Stem Cells (MSC).

  • Yes, CellBri instruments are being used in over 100 pipeline products in China and with some commercially approved cell therapy products as well.

  • Though we currently manufacture everything in China, we have warehouse locations in Kansas City, MO and in Budapest, Hungary that serve our North America and European customers, respectively. We can ship products to customers in these regions in 3-5 business days.

  • Yes, air is automatically removed (“burped”) from the bags after dispensing using the Gentle P-Pac. The bubble volume can be controlled within 5µl.

  • Our instruments are manufactured at our headquarters in China’s tech hub, Shenzhen. Our consumables are manufactured in our new factory, in Changzhou City, China. Between these two facilities, we have the capacity to build 5000 instruments and assemble half a million tubing sets per year.

  • Yes, CellBri is actively seeking collaborations and partnerships with both therapeutic companies and tool providers. As a company, our primary goal is to reduce the overall cost of cell therapy manufacturing and drive meaningful progress across the industry.

    We believe the most effective way to achieve this is by partnering with organizations that have made significant advancements in areas outside our core specialty. We are dedicated to working alongside the companies and service providers that therapy developers already trust or plan to integrate into their workflows to create a more seamless and efficient manufacturing ecosystem.

Partner With Us

We believe automation should empower—not limit—your vision. Join the growing number of teams using CellBri to accelerate their therapies and unlock smarter, safer, and more scalable production.